张玉明，博士，副教授，硕导，江苏省科技副总。南京大学博士，师从何卫江教授和郭子建院士。主要致力于开发多模态分子探针应用于活体成像示踪，靶向型分子应用于成像指导下的中子捕获治疗。迄今已在Nat.Commun., JACS, Anal. Chem.等学术期刊发表SCI论文20余篇，获授权发明专利2项。主持国家级和省市级科研项目3项，作为核心成员参与国家重点研发计划青年项目1项。指导江苏省老员工创新创业训练计划项目2项。

Email: zym81@ntu.edu.cn。

    主持的科研项目：

1. 国家自然科学基金青年项目，22107054，靶向活体周期性缺氧探测的荧光-光声双模式比率探针的构筑，已结项，主持；

2. 南通市科技计划项目，JC2021114，检测生命体周期性缺氧的荧光-光声双模式比率探针的构筑，已结项，主持；

3. 江苏省产学研合作项目，BY2020569，2020-2023，已结项，主持；

    近期发表的学术论文：

1. Yuming Zhang, Wenxuan Zhao, Yuncong Chen*, Hao Yuan, Hongbao Fang, Shankun Yao, Changli Zhang, Hongxia Xu, Nan Li, Zhipeng Liu, Zijian Guo*, Qingshun Zhao*, Yong Liang & Weijiang He*, Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo, Nat. Commun., 2021, 12, 772. (一作，IF: 17.69, 一区)

2. Yanxi Liu, Qu Tang, Yuming Zhang*, Mengjia Xu, Yong Yao, Yuling Qin, Quan Liu*, and Li Wu*, A Ratiometric Fluorescent Probe with Reversible Redox-Response for Monitoring Dynamic Release of H2S Donors, Anal. Chem., 2025, 97, 10611−10618. (通讯，IF: 6.7, 一区)

3. Anli Pan, Xijuan Gu, Wenjun Ming, Jing Zhang, Wenjun Jiang, Yuming Zhang*, Shanshan Wang*, Yuling Qin, Li Wu*, miRNA biomarkers: advancing early detection of acute myocardial Infarction, Microchimica Acta, 2025, 192, 500. (通讯，IF: 5.3, 二区)

4. Yanxi Liu, Mengjia Xu, Haonan Chen, Quan Liu*, Yuming Zhang*, A fluorescent‐colorimetric probe for peroxynitrite‐anion‐imaging in living cells, Chinese J. Inorg. Chem., 2025, 41, 1112-1122. (通讯，IF: 0.7, 三区)

5. Yuming Zhang, Yuncong Chen*, Hongbao Fang, Yanjun Wang, Shumeng Li, Hao Yuan, Shankun Yao, Shuheng Qin, Weijiang He* and Zijian Guo, A ratiometric pH probe for acidification tracking in dysfunctional mitochondria and tumour tissue in vivo, J. Mater. Chem. B., 2022, 10, 5422. (一作，IF: 7.57, 二区)

5. Yuming Zhang, Yuncong Chen*, Xiangchao Shi, Yang Bai, Weijiang He* and Zijian Guo, A sensitive and ratiometric fluorescent probe for imaging cytosolic H2S generation, New J. Chem., 2022, 46, 21464. (一作，IF: 3.9, 三区)

6. Yuming Zhang, Yuncong Chen*, Yang Bai, Xuling Xue, Weijiang He*, Zijian Guo, FRET-based fluorescent ratiometric probes for the rapid detection of endogenous hydrogen sulphide in living cells, Analyst, 2020, 145, 4233-4238. (一作，IF: 4.2, 二区)

7. Yuming Zhang, Yuncong Chen*, Hongbao Fang, Xiangchao Shi, Hao Yuan, Yang Bai, Weijiang He*, Zijian Guo, A ratiometric fluorescent probe for imaging enzyme dependent hydrogen sulfide variation in the mitochondria and in living mice, Analyst, 2020, 145, 5123-5127. (一作，IF: 4.2, 二区)

    获授权的发明专利：

1. 张玉明；刘晏希；吴丽；秦玉岭；刘泉；一种比率型可逆响应的硫化氢荧光探针及其合成方法与应用，2025-09-30, 中国，ZL 2024 1 305526. 0

2. 何卫江；陈韵聪；郭子建；张玉明；方红宝；一种乏氧荧光探针及其应用，2022-04-22，中国，ZL 2019 1 1049087.0